Transcription and FACT facilitate the restoration of replication-coupled chromatin assembly defects

Genome duplication occurs through the coordinated action of DNA replication and nucleosome assembly at replication forks. Defective nucleosome assembly causes DNA lesions by fork breakage that need to be repaired. In addition, it causes a loss of chromatin integrity. These chromatin alterations can...

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Detalles Bibliográficos
Autores principales: Barrientos-Moreno, Marta, Maya-Miles, Douglas, Murillo-Pineda, Marina, Fontalva, Sara, Pérez-Alegre, Mónica, Andujar, Eloísa, Prado, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349138/
https://www.ncbi.nlm.nih.gov/pubmed/37452085
http://dx.doi.org/10.1038/s41598-023-38280-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349138/
https://www.ncbi.nlm.nih.gov/pubmed/37452085
http://dx.doi.org/10.1038/s41598-023-38280-w

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