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Transcription and FACT facilitate the restoration of replication-coupled chromatin assembly defects
Genome duplication occurs through the coordinated action of DNA replication and nucleosome assembly at replication forks. Defective nucleosome assembly causes DNA lesions by fork breakage that need to be repaired. In addition, it causes a loss of chromatin integrity. These chromatin alterations can...
Autores principales: | Barrientos-Moreno, Marta, Maya-Miles, Douglas, Murillo-Pineda, Marina, Fontalva, Sara, Pérez-Alegre, Mónica, Andujar, Eloísa, Prado, Félix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349138/ https://www.ncbi.nlm.nih.gov/pubmed/37452085 http://dx.doi.org/10.1038/s41598-023-38280-w |
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