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Effectiveness and safety of anti-IL-5/Rα biologics in eosinophilic granulomatosis with polyangiitis: a two-year multicenter observational study

BACKGROUND: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis characterized by asthma, systemic manifestations, and blood and tissue eosinophilia. OBJECTIVE: To assess the effectiveness and safety of mepolizumab (anti-IL-5) and benralizumab (anti-IL-5Rα) in EGPA for 24 months...

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Detalles Bibliográficos
Autores principales: Nolasco, Santi, Portacci, Andrea, Campisi, Raffaele, Buonamico, Enrico, Pelaia, Corrado, Benfante, Alida, Triggiani, Massimo, Spadaro, Giuseppe, Caiaffa, Maria Filomena, Scioscia, Giulia, Detoraki, Aikaterini, Valenti, Giuseppe, Papia, Francesco, Tomasello, Alessandra, Crimi, Nunzio, Scichilone, Nicola, Pelaia, Girolamo, Carpagnano, Giovanna Elisiana, Crimi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349177/
https://www.ncbi.nlm.nih.gov/pubmed/37457743
http://dx.doi.org/10.3389/fimmu.2023.1204444