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Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolution
Androgen deprivation therapy is a cornerstone of treatment for advanced prostate cancer, and the development of castrate-resistant prostate cancer (CRPC) is the primary cause of prostate cancer-related mortality. While CRPC typically develops through a gain in androgen receptor (AR) signaling, a sub...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349394/ https://www.ncbi.nlm.nih.gov/pubmed/37455903 http://dx.doi.org/10.3389/fendo.2023.1191311 |