Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolution

Androgen deprivation therapy is a cornerstone of treatment for advanced prostate cancer, and the development of castrate-resistant prostate cancer (CRPC) is the primary cause of prostate cancer-related mortality. While CRPC typically develops through a gain in androgen receptor (AR) signaling, a sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Imamura, Jarrell, Ganguly, Shinjini, Muskara, Andrew, Liao, Ross S., Nguyen, Jane K., Weight, Christopher, Wee, Christopher E., Gupta, Shilpa, Mian, Omar Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349394/
https://www.ncbi.nlm.nih.gov/pubmed/37455903
http://dx.doi.org/10.3389/fendo.2023.1191311

Ejemplares similares

Ejemplares similares