The malaria blood stage antigen PfCyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in experimental animals

BACKGROUND: Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex protein essential for erythrocyte invasion. In contrast to several previously clinically tested merozoite vaccine candidate antigens, PfCyRPA is not polymorphic, making it a promising candidate antige...

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Detalles Bibliográficos
Autores principales: Tamborrini, Marco, Schäfer, Anja, Hauser, Julia, Zou, Linghui, Paris, Daniel H., Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349406/
https://www.ncbi.nlm.nih.gov/pubmed/37454145
http://dx.doi.org/10.1186/s12936-023-04638-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349406/
https://www.ncbi.nlm.nih.gov/pubmed/37454145
http://dx.doi.org/10.1186/s12936-023-04638-8

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