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Overexpression of POLA2 in hepatocellular carcinoma is involved in immune infiltration and predicts a poor prognosis

BACKGROUND: Hepatocellular carcinoma (HCC) is the second malignancy worldwide. POLA2 initiates DNA replication, regulates cell cycle and gene repair that promote tumorigenesis and disease progression. However, the prognostic and biological function roles of POLA2 in HCC had not been conclusively det...

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Detalles Bibliográficos
Autores principales: Liu, Long, Wang, Qi, Wu, Linjun, Zhang, Lele, Huang, Yuxi, Yang, Haihua, guo, Le, Fang, Zheping, Wang, Xuequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349470/
https://www.ncbi.nlm.nih.gov/pubmed/37452331
http://dx.doi.org/10.1186/s12935-023-02949-z