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From frozen cell bank to product assay: high-throughput strain characterisation for autonomous Design-Build-Test-Learn cycles

BACKGROUND: Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, including cultivation and analytics, is crucial in the Test phase. Here, we present t...

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Detalles Bibliográficos
Autores principales: Helleckes, Laura M., Puchta, Debora, Czech, Hannah, Morschett, Holger, Geinitz, Bertram, Wiechert, Wolfgang, Oldiges, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349472/
https://www.ncbi.nlm.nih.gov/pubmed/37452397
http://dx.doi.org/10.1186/s12934-023-02140-z