Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons

Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content. The MHC genes have expanded in passerine birds, resulting in...

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Detalles Bibliográficos
Autores principales: Mellinger, Samantha, Stervander, Martin, Lundberg, Max, Drews, Anna, Westerdahl, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349553/
https://www.ncbi.nlm.nih.gov/pubmed/37456901
http://dx.doi.org/10.7717/peerj.15480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349553/
https://www.ncbi.nlm.nih.gov/pubmed/37456901
http://dx.doi.org/10.7717/peerj.15480

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