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Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons
Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content. The MHC genes have expanded in passerine birds, resulting in...
Autores principales: | Mellinger, Samantha, Stervander, Martin, Lundberg, Max, Drews, Anna, Westerdahl, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349553/ https://www.ncbi.nlm.nih.gov/pubmed/37456901 http://dx.doi.org/10.7717/peerj.15480 |
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