Design, Synthesis and Biological Evaluation of Glycosylated Derivatives of Silibinin as Potential Anti-Tumor Agents

OBJECTIVE: Silibinin, a natural product extracted from the seeds of the Silybum marianum, is versatile with various pharmacological effects. However, its clinical application was strongly hampered by its low bioavailability and poor water solubility. Herein, a series of glycosylated silibinin deriva...

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Detalles Bibliográficos
Autores principales: Xi, Jian-Jun, Cao, Yu, He, Ruo-Yu, Zhang, Jian-Kang, Zhao, Yan-Mei, Tong, Qiao, Bao, Jian-Feng, Dong, Yi-Chen, Zhuang, Rang-Xiao, Huang, Jin-Song, Chen, Yongping, Liu, Shou-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349574/
https://www.ncbi.nlm.nih.gov/pubmed/37457888
http://dx.doi.org/10.2147/DDDT.S404036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349574/
https://www.ncbi.nlm.nih.gov/pubmed/37457888
http://dx.doi.org/10.2147/DDDT.S404036

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