Co-culture with normal and senescent AC16 cardiomyocytes modulates fibrotic response in primary human ventricular fibroblasts

Transwell co-culture with human AC16 cardiomyocyte-like cells modifies the response of primary human ventricular fibroblasts to TGF-β stimulation. Fibrotic response markers including collagen I (COL1A1) and ɑ-smooth muscle actin (ACTA2) are amplified in the presence of AC16 cells, whereas others inc...

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Detalles Bibliográficos
Autores principales: Hidalgo, Veronica, Kastury, Nikhitha, Durham, Cheyanne W., Currie, Jordan, Amaya, Milton, Lam, Maggie P. Y., Lau, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349648/
https://www.ncbi.nlm.nih.gov/pubmed/37456138
http://dx.doi.org/10.17912/micropub.biology.000864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349648/
https://www.ncbi.nlm.nih.gov/pubmed/37456138
http://dx.doi.org/10.17912/micropub.biology.000864

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