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Characterization of Genetic Mutations in Multi-Drug-Resistant Isolates of Mycobacterium tuberculosis Bacilli Conferring Resistance to a Second-Line Anti-tuberculosis Drug

Introduction: Multi-drug-resistant tuberculosis (MDR-TB) has become a major public health concern globally. Mutations in first- and second-line drug targets such as katG, inhA, rpoB, rrs, eis, gyrA, and gyrB have been associated with drug resistance. Monitoring predominant mutations in the MDR-TB pa...

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Detalles Bibliográficos
Autores principales: Sharma, Raj Kishor, Kumari, Usha, Kumari, Namrata, Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349655/
https://www.ncbi.nlm.nih.gov/pubmed/37456413
http://dx.doi.org/10.7759/cureus.40442