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Clozapine but not lithium reverses aberrant tyrosine uptake in patients with bipolar disorder

RATIONALE: Availability of the dopamine and noradrenaline precursor tyrosine is critical for normal functioning, and deficit in tyrosine transport across cell membrane and the blood-brain barrier has been reported in bipolar disorder and schizophrenia. Clozapine and lithium are two psychoactive agen...

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Detalles Bibliográficos
Autores principales: Tabrisi, R, Harun-Rashid, MD, Montero, J, Venizelos, N, Msghina, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349740/
https://www.ncbi.nlm.nih.gov/pubmed/37318540
http://dx.doi.org/10.1007/s00213-023-06397-5