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Clozapine but not lithium reverses aberrant tyrosine uptake in patients with bipolar disorder
RATIONALE: Availability of the dopamine and noradrenaline precursor tyrosine is critical for normal functioning, and deficit in tyrosine transport across cell membrane and the blood-brain barrier has been reported in bipolar disorder and schizophrenia. Clozapine and lithium are two psychoactive agen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349740/ https://www.ncbi.nlm.nih.gov/pubmed/37318540 http://dx.doi.org/10.1007/s00213-023-06397-5 |