Correlation of N-acetyltransferase 2 genotype and acetylation status with plasma isoniazid concentration and its metabolic ratio in ethiopian tuberculosis patients

Unfavorable treatment outcomes for tuberculosis (TB) treatment might result from altered plasma exposure to antitubercular drugs in TB patients. The present study investigated the distribution of the N-Acetyltransferase 2 (NAT2) genotype, isoniazid acetylation status, genotype–phenotype concordance...

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Detalles Bibliográficos
Autores principales: Sileshi, Tesemma, Telele, Nigus Fikrie, Burkley, Victoria, Makonnen, Eyasu, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349800/
https://www.ncbi.nlm.nih.gov/pubmed/37454203
http://dx.doi.org/10.1038/s41598-023-38716-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349800/
https://www.ncbi.nlm.nih.gov/pubmed/37454203
http://dx.doi.org/10.1038/s41598-023-38716-3

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