Cargando…

PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation

Polymerase 1 and transcript release factor (PTRF, encoding by Cavin-1) regulates interleukin 33 (IL-33) release, which is implicated in asthma development. Z-DNA binding protein 1 (ZBP1)-sensing Z-RNAs induces necroptosis which causes inflammatory diseases. House dust mite (HDM) is the major source...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Juan, Liu, Yahui, Lan, Gelei, Zhou, Yao, Ni, Yingmeng, Liao, Kai, Zheng, Fang, Cheng, Qijian, Shi, Guochao, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349813/
https://www.ncbi.nlm.nih.gov/pubmed/37454215
http://dx.doi.org/10.1038/s41419-023-05971-1