Diacerein ameliorates cholestasis-induced liver fibrosis in rat via modulating HMGB1/RAGE/NF-κB/JNK pathway and endoplasmic reticulum stress

Diacerein is an interleukin (IL)-1β inhibitor approved for osteoarthritis. This study aimed to investigate the potential anti-fibrotic effect of diacerein against bile duct ligation (BDL)-induced liver fibrosis. Forty male Wistar rats were divided into: sham-operated group, BDL group, and BDL groups...

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Detalles Bibliográficos
Autores principales: Abdelfattah, Amira Mohammed, Mahmoud, Shireen Sami, EL-wafaey, Dalia Ibrahim, Abdelgeleel, Heba Mahmoud, Abdelhamid, Amira Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349817/
https://www.ncbi.nlm.nih.gov/pubmed/37454204
http://dx.doi.org/10.1038/s41598-023-38375-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349817/
https://www.ncbi.nlm.nih.gov/pubmed/37454204
http://dx.doi.org/10.1038/s41598-023-38375-4

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