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The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel

Divalent cation block is observed in various tetrameric ion channels. For blocking, a divalent cation is thought to bind in the ion pathway of the channel, but such block has not yet been directly observed. So, the behaviour of these blocking divalent cations remains still uncertain. Here, we elucid...

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Detalles Bibliográficos
Autores principales: Irie, Katsumasa, Oda, Yoshinori, Sumikama, Takashi, Oshima, Atsunori, Fujiyoshi, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349818/
https://www.ncbi.nlm.nih.gov/pubmed/37454189
http://dx.doi.org/10.1038/s41467-023-39987-0