mRNA lipid nanoparticle-mediated pyroptosis sensitizes immunologically cold tumors to checkpoint immunotherapy

Synergistically improving T-cell responsiveness is promising for favorable therapeutic outcomes in immunologically cold tumors, yet current treatments often fail to induce a cascade of cancer-immunity cycle for effective antitumor immunity. Gasdermin-mediated pyroptosis is a newly discovered mechani...

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Detalles Bibliográficos
Autores principales: Li, Fengqiao, Zhang, Xue-Qing, Ho, William, Tang, Maoping, Li, Zhongyu, Bu, Lei, Xu, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349854/
https://www.ncbi.nlm.nih.gov/pubmed/37454146
http://dx.doi.org/10.1038/s41467-023-39938-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349854/
https://www.ncbi.nlm.nih.gov/pubmed/37454146
http://dx.doi.org/10.1038/s41467-023-39938-9

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