A large-scale Boolean model of the rheumatoid arthritis fibroblast-like synoviocytes predicts drug synergies in the arthritic joint

Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology. However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in initiating and perpetuating destructive joint inflammation by expressing immuno-modulating cytokines, adhesion molecules...

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Detalles Bibliográficos
Autores principales: Singh, Vidisha, Naldi, Aurelien, Soliman, Sylvain, Niarakis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349856/
https://www.ncbi.nlm.nih.gov/pubmed/37454172
http://dx.doi.org/10.1038/s41540-023-00294-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349856/
https://www.ncbi.nlm.nih.gov/pubmed/37454172
http://dx.doi.org/10.1038/s41540-023-00294-5

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