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HIV-1 promotes ubiquitination of the amyloidogenic C-terminal fragment of APP to support viral replication

HIV-1 replication in macrophages and microglia involves intracellular assembly and budding into modified subsets of multivesicular bodies (MVBs), which support both viral persistence and spread. However, the cellular factors that regulate HIV-1’s vesicular replication remain poorly understood. Recen...

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Detalles Bibliográficos
Autores principales: Gu, Feng, Boisjoli, Marie, Naghavi, Mojgan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349857/
https://www.ncbi.nlm.nih.gov/pubmed/37454116
http://dx.doi.org/10.1038/s41467-023-40000-x