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Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma

A variety of mutational processes drive cancer development, but their dynamics across the entire disease spectrum from pre-cancerous to advanced neoplasia are poorly understood. We explore the mutagenic processes shaping oesophageal adenocarcinoma tumorigenesis in 997 instances comprising distinct s...

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Detalles Bibliográficos
Autores principales: Abbas, Sujath, Pich, Oriol, Devonshire, Ginny, Zamani, Shahriar A., Katz-Summercorn, Annalise, Killcoyne, Sarah, Cheah, Calvin, Nutzinger, Barbara, Grehan, Nicola, Lopez-Bigas, Nuria, Fitzgerald, Rebecca C., Secrier, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349863/
https://www.ncbi.nlm.nih.gov/pubmed/37454136
http://dx.doi.org/10.1038/s41467-023-39957-6