Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons

Immunotherapy has become established as major treatment modality for multiple types of solid tumors, including colorectal cancer. Identifying novel immunotherapeutic targets to enhance anti-tumor immunity and sensitize current immune checkpoint blockade (ICB) in colorectal cancer is needed. Here we...

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Detalles Bibliográficos
Autores principales: Liu, Yanan, Hu, Longmiao, Wu, Zhengzhen, Yuan, Kun, Hong, Guangliang, Lian, Zhengke, Feng, Juanjuan, Li, Na, Li, Dali, Wong, Jiemin, Chen, Jiekai, Liu, Mingyao, He, Jiangping, Pang, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349869/
https://www.ncbi.nlm.nih.gov/pubmed/37454216
http://dx.doi.org/10.1038/s41467-023-39943-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349869/
https://www.ncbi.nlm.nih.gov/pubmed/37454216
http://dx.doi.org/10.1038/s41467-023-39943-y

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