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Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons
Immunotherapy has become established as major treatment modality for multiple types of solid tumors, including colorectal cancer. Identifying novel immunotherapeutic targets to enhance anti-tumor immunity and sensitize current immune checkpoint blockade (ICB) in colorectal cancer is needed. Here we...
Autores principales: | Liu, Yanan, Hu, Longmiao, Wu, Zhengzhen, Yuan, Kun, Hong, Guangliang, Lian, Zhengke, Feng, Juanjuan, Li, Na, Li, Dali, Wong, Jiemin, Chen, Jiekai, Liu, Mingyao, He, Jiangping, Pang, Xiufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349869/ https://www.ncbi.nlm.nih.gov/pubmed/37454216 http://dx.doi.org/10.1038/s41467-023-39943-y |
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