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The human acetylcholinesterase C-terminal T30 peptide activates neuronal growth through alpha 7 nicotinic acetylcholine receptors and the mTOR pathway

Acetylcholinesterase (AChE) is a highly conserved enzyme responsible for the regulation of acetylcholine signaling within the brain and periphery. AChE has also been shown to participate in non-enzymatic activity and contribute to cellular development and aging. In particular, enzymatic cleavage of...

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Detalles Bibliográficos
Autores principales: Graur, Alexandru, Sinclair, Patricia, Schneeweis, Amanda K., Pak, Daniel T., Kabbani, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349870/
https://www.ncbi.nlm.nih.gov/pubmed/37454238
http://dx.doi.org/10.1038/s41598-023-38637-1