Fatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation

DNA repair is a tightly coordinated stress response to DNA damage, which is critical for preserving genome integrity. Accruing evidence suggests that metabolic pathways have been correlated with cellular response to DNA damage. Here, we show that fatty acid oxidation (FAO) is a crucial regulator of...

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Detalles Bibliográficos
Autores principales: Yang, Seungyeon, Hwang, Sunsook, Kim, Byungjoo, Shin, Seungmin, Kim, Minjoong, Jeong, Seung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349888/
https://www.ncbi.nlm.nih.gov/pubmed/37454129
http://dx.doi.org/10.1038/s41419-023-05968-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349888/
https://www.ncbi.nlm.nih.gov/pubmed/37454129
http://dx.doi.org/10.1038/s41419-023-05968-w

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