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Mesenchymal Vangl facilitates airway elongation and widening independently of the planar cell polarity complex

A hallmark of mammalian lungs is the fractal nature of the bronchial tree. In the adult, each successive generation of airways is a fraction of the size of the parental branch. This fractal structure is physiologically beneficial, as it minimizes the energy needed for breathing. Achieving this patte...

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Detalles Bibliográficos
Autores principales: Paramore, Sarah V., Goodwin, Katharine, Devenport, Danelle, Nelson, Celeste M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349956/
https://www.ncbi.nlm.nih.gov/pubmed/37461477
http://dx.doi.org/10.1101/2023.07.03.547543