Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation

Treatment-refractory severe asthma manifests a neutrophilic phenotype associated with TH17 responses. Heightened unfolded protein responses (UPRs) are associated with the risk of asthma, including severe asthma. However, how UPRs participate in the deregulation of TH17 cells leading to this type of...

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Detalles Bibliográficos
Autores principales: Wu, Dandan, Zhang, Xing, Zimmerly, Kourtney M., Wang, Ruoning, Livingston, Amanda, Iwawaki, Takao, Kumar, Ashok, Wu, Xiang, Mandell, Michael A., Liu, Meilian, Yang, Xuexian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349957/
https://www.ncbi.nlm.nih.gov/pubmed/37461622
http://dx.doi.org/10.1101/2023.06.30.547286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349957/
https://www.ncbi.nlm.nih.gov/pubmed/37461622
http://dx.doi.org/10.1101/2023.06.30.547286

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