Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects: Distributions of fitness effects of spontaneous mutations

The fitness effects of new mutations determine key properties of evolutionary processes. Beneficial mutations drive evolution, yet selection is also shaped by the frequency of small-effect deleterious mutations, whose combined effect can burden otherwise adaptive lineages and alter evolutionary traj...

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Detalles Bibliográficos
Autores principales: Plavskin, Yevgeniy, de Biase, Maria Stella, Ziv, Naomi, Janská, Libuše, Zhu, Yuan O., Hall, David W., Schwarz, Roland F, Tranchina, Daniel, Siegal, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349969/
https://www.ncbi.nlm.nih.gov/pubmed/37461506
http://dx.doi.org/10.1101/2023.07.04.547687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349969/
https://www.ncbi.nlm.nih.gov/pubmed/37461506
http://dx.doi.org/10.1101/2023.07.04.547687

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