Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors

Tumor-reactive CD8 T cells found in cancer patients are frequently dysfunctional, unable to halt tumor growth. Adoptive T cell transfer (ACT), the administration of large numbers of in vitro-generated cytolytic tumor-reactive CD8 T cells, is an important cancer immune therapy being pursued. However,...

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Detalles Bibliográficos
Autores principales: Espinosa-Carrasco, Gabriel, Scrivo, Aurora, Zumbo, Paul, Dave, Asim, Betel, Doron, Hellmann, Matthew, Burt, Bryan M, Lee, Hyun-Sung, Schietinger, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349998/
https://www.ncbi.nlm.nih.gov/pubmed/37461721
http://dx.doi.org/10.1101/2023.07.03.547423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349998/
https://www.ncbi.nlm.nih.gov/pubmed/37461721
http://dx.doi.org/10.1101/2023.07.03.547423

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