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Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors
Tumor-reactive CD8 T cells found in cancer patients are frequently dysfunctional, unable to halt tumor growth. Adoptive T cell transfer (ACT), the administration of large numbers of in vitro-generated cytolytic tumor-reactive CD8 T cells, is an important cancer immune therapy being pursued. However,...
Autores principales: | Espinosa-Carrasco, Gabriel, Scrivo, Aurora, Zumbo, Paul, Dave, Asim, Betel, Doron, Hellmann, Matthew, Burt, Bryan M, Lee, Hyun-Sung, Schietinger, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349998/ https://www.ncbi.nlm.nih.gov/pubmed/37461721 http://dx.doi.org/10.1101/2023.07.03.547423 |
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