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Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples

Accurate detection of somatic mutations in DNA sequencing data is a fundamental prerequisite for cancer research. Previous analytical challenge was overcome by consensus mutation calling from four to five popular callers. This, however, increases the already nontrivial computing time from individual...

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Detalles Bibliográficos
Autores principales: Ji, Shuangxi, Zhu, Tong, Sethia, Ankit, Wang, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350007/
https://www.ncbi.nlm.nih.gov/pubmed/37461467
http://dx.doi.org/10.1101/2023.07.04.547569