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Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions
Structural and functional studies of the ATP-binding cassette transporter MsbA have revealed two distinct lipopolysaccharide (LPS) binding sites: one located in the central cavity and the other at a membrane-facing, exterior site. Although these binding sites are known to be important for MsbA funct...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350010/ https://www.ncbi.nlm.nih.gov/pubmed/37461710 http://dx.doi.org/10.1101/2023.07.03.547565 |