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Dynamic landscape of the intracellular termini of acid-sensing ion channel 1a

Acid-sensing ion channels (ASICs) are trimeric proton-gated sodium channels. Recently it has been shown that these channels play a role in necroptosis following prolonged acidic exposure like occurs in stroke. The C-terminus of the channel is thought to mediate necroptotic cell death through interac...

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Detalles Bibliográficos
Autores principales: Cullinan, Megan M., Klipp, Robert C., Camenisch, Abigail, Bankston, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350031/
https://www.ncbi.nlm.nih.gov/pubmed/37461628
http://dx.doi.org/10.1101/2023.07.05.547693