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Multimodal hierarchical classification of CITE-seq data delineates immune cell states across lineages and tissues

Single-cell RNA sequencing (scRNA-seq) is invaluable for profiling cellular heterogeneity and dissecting transcriptional states, but transcriptomic profiles do not always delineate subsets defined by surface proteins, as in cells of the immune system. Cellular Indexing of Transcriptomes and Epitopes...

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Detalles Bibliográficos
Autores principales: Caron, Daniel P., Specht, William L., Chen, David, Wells, Steven B., Szabo, Peter A., Jensen, Isaac J., Farber, Donna L., Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350048/
https://www.ncbi.nlm.nih.gov/pubmed/37461466
http://dx.doi.org/10.1101/2023.07.06.547944