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Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity

Epoxyoctadecamonoenoic acids (EpOMEs) are epoxide derivatives of linoleic acid (9,12-octadecadienoic acid: LA). They are metabolized into dihydroxyoctadecamonoenoic acids (DiHOMEs) in mammals. Unlike in mammals where they act as adipokines or lipokines, EpOMEs act as immunosuppressants in insects. H...

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Detalles Bibliográficos
Autores principales: Hrithrik, Tafim Hossain, Lee, Dong-Hee, Singh, Nalin, Vik, Anders, Hammock, Bruce D., Kim, Yonggyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350063/
https://www.ncbi.nlm.nih.gov/pubmed/37461499
http://dx.doi.org/10.1101/2023.07.07.548078