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The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons

Cancers showing excessive innervation of sensory neurons (SN) in their microenvironments are associated with poor outcomes due to promoted growth, increased tumor recurrence, metastasis, and cancer pain, suggesting SNs play a regulatory role in cancer aggressiveness. Using a preclinical model in whi...

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Detalles Bibliográficos
Autores principales: OKUI, TATSUO, Hiasa, Masahiro, Hata, Kenji, Roodman, G David, Nakanishi, Masako, Yoneda, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350177/
https://www.ncbi.nlm.nih.gov/pubmed/37461623
http://dx.doi.org/10.21203/rs.3.rs-3105966/v1