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The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons
Cancers showing excessive innervation of sensory neurons (SN) in their microenvironments are associated with poor outcomes due to promoted growth, increased tumor recurrence, metastasis, and cancer pain, suggesting SNs play a regulatory role in cancer aggressiveness. Using a preclinical model in whi...
Autores principales: | OKUI, TATSUO, Hiasa, Masahiro, Hata, Kenji, Roodman, G David, Nakanishi, Masako, Yoneda, Toshiyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350177/ https://www.ncbi.nlm.nih.gov/pubmed/37461623 http://dx.doi.org/10.21203/rs.3.rs-3105966/v1 |
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