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Broad Protection Against Clade 1 Sarbecoviruses After a Single Immunization with Cocktail Spike-Protein-Nanoparticle Vaccine

The 2002 SARS outbreak, the 2019 emergence of COVID-19, and the continuing evolution of immune-evading SARS-CoV-2 variants together highlight the need for a broadly protective vaccine against ACE2-utilizing sarbecoviruses. While updated variant-matched formulations such as Pfizer-BioNTech’s bivalent...

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Detalles Bibliográficos
Autores principales: Halfmann, Peter J., Loeffler, Kathryn, Duffy, Augustine, Kuroda, Makoto, Kawaoka, Yoshihiro, Kane, Ravi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350183/
https://www.ncbi.nlm.nih.gov/pubmed/37461652
http://dx.doi.org/10.21203/rs.3.rs-3088907/v1