Apoer2-ICD-dependent regulation of hippocampal ribosome mRNA loading

BACKGROUND: ApoE4, the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), sequesters a pro-synaptogenic Reelin receptor, Apoer2, in the endosomal compartment and prevents its normal recycling. In the adult brain, Reelin potentiates excitatory synapses and thereby protects...

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Detalles Bibliográficos
Autores principales: Wasser, Catherine, Werthmann, Gordon C., Hall, Eric M, Kuhbandner, Kristina, Wong, Connie H, Durakoglugil, Murat S, Herz, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350194/
https://www.ncbi.nlm.nih.gov/pubmed/37461529
http://dx.doi.org/10.21203/rs.3.rs-3040567/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350194/
https://www.ncbi.nlm.nih.gov/pubmed/37461529
http://dx.doi.org/10.21203/rs.3.rs-3040567/v1

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