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Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays

DNA methylation (DNAm) plays a crucial role in a number of complex diseases. However, the reliability of DNAm levels measured using Illumina arrays varies across different probes. Previous research primarily assessed probe reliability by comparing duplicate samples between the 450k-450k or 450k-EPIC...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Lukacsovich, David, Varma, Achintya, Chen, X. Steven, Kunkle, Brian, Martin, Eden R., Wang, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350239/
https://www.ncbi.nlm.nih.gov/pubmed/37461726
http://dx.doi.org/10.21203/rs.3.rs-3068938/v2