Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease

BACKGROUND: Thiopurines continue to play an important role in the treatment of inflammatory bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. Especially, hematopoietic toxicity may lead to severe agranulocytosis. In a previous prospective study, we investiga...

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Detalles Bibliográficos
Autores principales: Suzuki, Shizuka, Uchiyama, Kan, Motoi, Yutaro, Yoshii, Yuuki, Inoue, Yukari, Kubota, Takahiro, Odahara, Shunichi, Ohtaki, Yuichiro, Takami, Shinichiro, Ito, Zensho, Sato, Nobuhiro, Ohkusa, Toshifumi, Koido, Shigeo, Saruta, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350251/
https://www.ncbi.nlm.nih.gov/pubmed/37454061
http://dx.doi.org/10.1186/s12876-023-02881-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350251/
https://www.ncbi.nlm.nih.gov/pubmed/37454061
http://dx.doi.org/10.1186/s12876-023-02881-6

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