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UTX deletion promotes M2 macrophage polarization by epigenetically regulating endothelial cell-macrophage crosstalk after spinal cord injury

Macrophages polarized to the M2 subtype after spinal cord injury (SCI) are beneficial for promoting neurological recovery. The crosstalk between endothelial cells (ECs) and macrophages is crucial for the imbalance between proinflammatory and pro-resolving responses caused by macrophage heterogeneity...

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Detalles Bibliográficos
Autores principales: Peng, Wei, Xie, Yong, Luo, Zixiang, Liu, Yudong, Xu, Jiaqi, Li, Chengjun, Qin, Tian, Lu, Hongbin, Hu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350278/
https://www.ncbi.nlm.nih.gov/pubmed/37454119
http://dx.doi.org/10.1186/s12951-023-01986-0