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Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos

Physiological hypoxia is critical for placental mammalian development. However, the underlying mechanisms by which hypoxia regulates embryonic development remain unclear. We discovered that the expression of glycolytic genes partially depends on hypoxia in neuroepithelial cells of E8.25 mouse embryo...

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Detalles Bibliográficos
Autores principales: Sakai, Daisuke, Murakami, Yuki, Shigeta, Daichi, Tomosugi, Mitsuhiro, Sakata-Haga, Hiromi, Hatta, Toshihisa, Shoji, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350492/
https://www.ncbi.nlm.nih.gov/pubmed/37465012
http://dx.doi.org/10.3389/fcell.2023.1212375