Cargando…
Structural basis of ubiquitin‐independent PP1 complex disassembly by p97
The AAA+‐ATPase p97 (also called VCP or Cdc48) unfolds proteins and disassembles protein complexes in numerous cellular processes, but how substrate complexes are loaded onto p97 and disassembled is unclear. Here, we present cryo‐EM structures of p97 in the process of disassembling a protein phospha...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350818/ https://www.ncbi.nlm.nih.gov/pubmed/37264685 http://dx.doi.org/10.15252/embj.2022113110 |