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HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion

Enhanced expression of the cold‐shock protein RNA binding motif 3 (RBM3) is highly neuroprotective both in vitro and in vivo. Whilst upstream signalling pathways leading to RBM3 expression have been described, the precise molecular mechanism of RBM3 cold induction remains elusive. To identify temper...

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Detalles Bibliográficos
Autores principales: Lin, Julie Qiaojin, Khuperkar, Deepak, Pavlou, Sofia, Makarchuk, Stanislaw, Patikas, Nikolaos, Lee, Flora CY, Zbiegly, Julia M, Kang, Jianning, Field, Sarah F, Bailey, David MD, Freeman, Joshua L, Ule, Jernej, Metzakopian, Emmanouil, Ruepp, Marc‐David, Mallucci, Giovanna R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350819/
https://www.ncbi.nlm.nih.gov/pubmed/37248947
http://dx.doi.org/10.15252/embj.2022113168