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Ca(2+)-stimulated ADCY1 and ADCY8 regulate distinct aspects of synaptic and cognitive flexibility
The type 1 and 8 adenylyl cyclase (ADCY1 and ADCY8) exclusively account for Ca(2+)-stimulated cyclic AMP (cAMP) production and regulate activity-dependent synaptic modification. In this study, we examined distinct forms of synaptic plasticity in the hippocampus of Adcy1(−/−) and Adcy8(−/−) mice. We...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351016/ https://www.ncbi.nlm.nih.gov/pubmed/37465213 http://dx.doi.org/10.3389/fncel.2023.1215255 |