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Obesity accelerates age defects in B cells, and weight loss improves B cell function

BACKGROUND: We have previously shown that obesity accelerates age-associated defects in B cell function and antibody production leading to decreased secretion of protective antibodies and increased autoimmunity. We wanted to evaluate if obese adults enrolled in a voluntary weight reduction program h...

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Detalles Bibliográficos
Autores principales: Frasca, Daniela, Romero, Maria, Diaz, Alain, Blomberg, Bonnie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351107/
https://www.ncbi.nlm.nih.gov/pubmed/37460937
http://dx.doi.org/10.1186/s12979-023-00361-9