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A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

BACKGROUND: Preterm birth (PTB), defined as delivery before 37 gestational weeks, imposes significant public health burdens. A recent maternal genome-wide association study of spontaneous PTB identified a noncoding locus near the angiotensin II receptor type 2 (AGTR2) gene. Genotype-Tissue Expressio...

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Detalles Bibliográficos
Autores principales: Wang, Li, Rossi, Robert M., Chen, Xiaoting, Chen, Jing, Runyon, Jilian, Chawla, Mehak, Miller, Daniel, Forney, Carmy, Lynch, Arthur, Zhang, Xuzhe, Kong, Fansheng, Jacobsson, Bo, Kottyan, Leah C., Weirauch, Matthew T., Zhang, Ge, Muglia, Louis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351137/
https://www.ncbi.nlm.nih.gov/pubmed/37455310
http://dx.doi.org/10.1186/s12916-023-02973-w