Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids

BACKGROUND: Approximately 20–50% of patients presenting with localized colorectal cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is a major prognostic determinant. Here, we have interrogated a heterogeneous set of primary colorectal cancer (CRC), liver CRC...

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Detalles Bibliográficos
Autores principales: Cioce, Mario, Fumagalli, Maria Rita, Donzelli, Sara, Goeman, Frauke, Canu, Valeria, Rutigliano, Daniela, Orlandi, Giulia, Sacconi, Andrea, Pulito, Claudio, Palcau, Alina Catalina, Fanciulli, Maurizio, Morrone, Aldo, Diodoro, Maria Grazia, Caricato, Marco, Crescenzi, Anna, Verri, Martina, Fazio, Vito Michele, Zapperi, Stefano, Levrero, Massimo, Strano, Sabrina, Grazi, Gian Luca, La Porta, Caterina, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351152/
https://www.ncbi.nlm.nih.gov/pubmed/37460938
http://dx.doi.org/10.1186/s13046-023-02754-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351152/
https://www.ncbi.nlm.nih.gov/pubmed/37460938
http://dx.doi.org/10.1186/s13046-023-02754-6

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